CRISPR-Cas9: Scientific Advances, Applications, and Ethical Challenges in Modern Genetics

CRISPR-Cas9: Scientific Advances and Applications

Authors

  • Taliha Ahmed Capital University of Science and Technology Islamabad
  • Fashi Ul Hassan Capital University of Science & Technology (CUST), Islamabad

DOI:

https://doi.org/10.69547/NS.32.05

Keywords:

CRISPR, Cas-9, Guide RNA, Gene editing, Designer Babies

Abstract

The advent of CRISPR-Cas9 represents a revolutionary advance in genome editing, offering unparalleled accuracy and efficiency in genetic modification. This review examines the fundamental ideas behind CRISPR-Cas9, its variants, its applications, and the effects it has had on a range of scientific fields. Since emerging as a groundbreaking biotechnological powerhouse, CRISPR-Cas9 has broadened its application to a variety of industries, including fundamental research, agriculture, and medicine. By carefully modifying disease-causing genes, a medical field has been developed with hitherto unheard-of possibilities for treating genetic illnesses. Through focused gene alterations, crop improvement in agriculture can be accelerated by improving yield, resilience, and nutritional content. It is impossible to overstate the tool's essential importance in comprehending gene activity and regulation in fundamental research. However, despite the enormous potential of CRISPR-Cas9, there are ethical concerns regarrding its use, particularly concerning human germline editing. By integrating scientific advances with ethical and policy perspectives, this review highlights CRISPR-Cas9’s innovative role in shaping the future of modern genetic engineering.

Additional Files

Published

2025-12-25

How to Cite

Ahmed, T., & Hassan, F. (2025). CRISPR-Cas9: Scientific Advances, Applications, and Ethical Challenges in Modern Genetics: CRISPR-Cas9: Scientific Advances and Applications. Nature’s Symphony , 3(2), 79–107. https://doi.org/10.69547/NS.32.05

Issue

Vol. 3 No. 2 (2025): Nature's Symphony - Volume 3, Issue 2

Section

Biology

License

Copyright (c) 2025 Taliha Ahmed, Fashi Hassan

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